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The Struther Arnott Lecture Series: 2021 Seminar

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Speakers

Terry Smith

Tracey Gloster

Polly Roy

Anabela Cordeiro da Silva

Bob Hancock

Blake Wiedenheft

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Hosted by

University of St Andrews

The University of St Andrews is a community of students, educators, and researchers, working together to address the biggest questions in science and society through world-leading research and teaching.

Posters

Graphical Abstracts

University of St Andrews

Poster 1 : Katrin Ackermann

Nanomolar pulse dipolar EPR spectroscopy in proteins

Poster 2 : Michaela Dermendjieva

Recombination, and then what? How Zika Virus Hybrids Improve Their Fitness

Poster 3 : Andri Vasou (Presented by David Hughes)

A co-opted ISG15-USP18 binding mechanism normally reserved for deISGylation controls type I IFN signalling

Poster 4 : Janie Olver

Exploring the role of the chromatin remodeller ATRX in C. elegans

Poster 5 : Chloe Jones

Development of a Novel CRISPR Screening Platform to Identify Antiviral Restriction Factors

Poster 6 : Maria Papa

Unveiling the structure of RNA using EPR Spectroscopy

Poster 7 : Chris Harding

Bypassing the requirements for aminoacyl-tRNA by a cyclodipeptide synthase enzyme

Poster 8 : Jane Hilton

Suppressing the Transmission of SARS-CoV2 Through Novel Surface Engineering

Poster 9 : Rachel Humann

Non-natural myristate analogues: Synthesis and their potent, selective activity upon bloodstream Trypanosoma brucei

Poster 10 : Callum Turner

Bifunctional probes targeting thioester domains from Gram positive bacteria

Poster 11 : Emmajay Sutherland

Using cyclodipeptide synthases to generate a library of diverse histidine-containing cyclic dipeptides

Poster 12 : Bobby Beaumont

Utilising Quantitative Interactomics to Identify Cellular Pathways Affected in Spinal Muscular Atrophy

Poster 13 : Andrew Seaton

The antiviral mechanism of ISGylation

Poster 14 : Martha Simpson

Exploring the role of the N-end rule in bacterial protein degradation and homeostasis

Poster 15 : Ben Read

Kinetic Characterisation of Catalysis and Inhibition of a Short-Form ATP-Phosphoribosyltransferase

Poster 16 : Stefania Pasare

Larval cells in Drosophila: death, extrusion and migration

Poster 17 : Joshua Wort

Dissociation Equilibria Studied by Pulse Dipolar EPR

Poster 18 : Michela Cerone

Exploring the activity and essentiality of the △-6 desaturase in Trypanosoma brucei

Poster 19 : Tiange Li

Monitoring the Formation and Disassembly of the Nanodiscs

Poster 20 : Kimberley Morrison

Neurochondrin: A potential therapeutic target in Motor Neurone Diseases?

Poster 21 : Laura Remmel

Investigating a fluoride sensing riboswitch by NMR and EPR

Poster 22 : Jianyi Mai

Larval epithelial cells migrate on the apical extracellular matrix during Drosophila morphogenesis

Poster 23 : Rebecca Woods

Triphenylphosphonium salts as antiparasitic agents

Poster 24 : Wanjia Yu

Inactivation for influenza A virus by 222 nm far-ultraviolet C light irradiation

Poster 25 : William Mosedale

Phenotype-directed discovery and functional characterisation of anti-protozoan compounds

Poster 26 : Zoe Barr

Characterisation of Farnesylated Protein 3; a novel component of plasmodesmata

Poster 27 : Gemma Fisher

Allosteric activation by re-organisation of the active-site

Poster 28 : Jens Tilsner

Candidate proteins for membrane constriction of the plasmodesmal endoplasmic reticulum

Poster 29 : Vanya Metodieva

Development of all-optical assays to study neurodegeneration in living brain slices

Poster 30 : Hannah Russell

DEER and RIDME measurements on a nitroxide spin-labelled, Cu(II)-bound protein

Poster 31 : Doris Chen

Aβ-induced alterations in the expression of Willin/FRMD6 underline its potential role in the pathogenesis of Alzheimer’s disease

Poster 32 : Stuart McQuarrie

Tetramerisation of the CRISPR ring nuclease Crn3/Csx3 facilitates cyclic oligoadenylate cleavage

Poster 33 : Rebekka Uhl & Stephen McMahon

Elucidating the physiological function of HexD

Poster 34 : Andrew Morton

Development of a high-throughput screening platform for all-optical stimulation and readout of neuronal activity

Poster 35 : Amelie Sobczak

Single molecule imaging of ACE2 in living cells

Poster 36 : Dongmei Wu

Probing Zn2+ HSA interactions using mutagenesis and isothermal titration calorimetry